120 CÁPSULAS DE 650 MG
Descrição: O Sinus-complex é uma fórmula tradicionalmente utilizada na América do Sul para alergias, sinusites, renites alérgicas e outros sintomas associados.
Usos Tradicionais: Em todo o tipo de complicações do foro respiratório, alergias, sinusites, renites.
Ingredientes: Urtica dioca, Baccharis genistelloides, Starchytarpheta jamaicensis, Bidens pilosa, Ilex paraguayiensis, hymeneia courbaril, Tabebuia impetiginosa, Mikania cordifolia.
Sugestão de uso:
Tome 2
cápsulas (650 mg cada) 3
x dia.
Contra-Indicações:
Não deve ser usado
durante a gravidez ou
durante a amamentação.
Interacções
medicamentosas: Nenhuma relatada.
Precauções:
•
Várias
plantas nesta fórmula foram documentadas
como hipotensoras
em estudos com animais. Indivíduos com pressão arterial
baixa devem ter
acompanhamento médico
para este possível efeito.
•
A erva
mate contém cafeína.
Pessoas
sensíveis ou alérgicas à cafeína devem evitar esta
fórmula ou começar com uma
dose baixa como teste.
• Gervâo contém uma pequena quantidade de ácido
salicílico. Os
alérgicos à aspirina ou ácido salicílico não devem
tomar
esta fórmula.
Deve ser tomada em conjunto com o Probiosan®
Propriedades: Antialérgicas, anti-histamínicas, antivirais e antibacterianas.
PESQUISAS E ESTUDOS PUBLICADOS POR PESQUISADORES SOBRE O SINUS-COMPLEX
Urtica dioica
A urtiga dioca
tradicionalmente usada para alergias e
confirmado pelos seguintes estudos:
Dar, S.,
et al. "Pharmacological and toxicological evaluation of
Urtica dioica." Pharm Biol. 2012
Oct 5. [Epub ahead of print]
Roschek, B., et al.
"Nettle extract (Urtica dioica) affects key receptors
and enzymes associated with allergic rhinitis."
Phytother Res. 2009 Jul;23(7):920-6.
Helms, S.,
et al. "Natural treatment of chronic rhinosinusitis."
Altern. Med. Rev. 2006 Sept; 11(3): 196-207.
Thornhill, S. M., et al. “Natural treatment of perennial
allergic rhinitis.” Altern. Med. Rev. 2000; 5(5):
448-54.
Galelli, A., et al. “Urtica dioica
agglutinin. A superantigenic lectin from stinging nettle
rhizome.” J. Immunol. 1993; 151(4): 1821-31.
Mittman, P. “Randomized, double-blind study of
freeze-dried Urtica dioica in the treatment of
allergic rhinitis.” Planta Med. 1990; 56(1):
44-7.
Carqueja (Baccharis sp)
Carqueja
tradicionalmente usada para alergias e sinusites e
confirmado pelos seguintes estudos:
de Oliveira,
C., et al. "Phenolic enriched extract of Baccharis
trimera presents anti-inflammatory and antioxidant
activities."
Molecules. 2012 Jan 23;17(1):1113-23.
Nogueira,
N., et al."In vitro and in vivo toxicological evaluation
of extract and fractions from Baccharis trimera with
anti-inflammatory activity." J Ethnopharmacol.
2011 Nov 18;138(2):513-22.
Paul, E., et al.
"Anti-inflammatory and Immunomodulatory Effects of
Baccharis trimera Aqueous Extract on Induced
Pleurisy in Rats and Lymphoproliferation In Vitro."
Inflammation. 2009 Sep 15.
Abad, M. J., et al.
“Anti-inflammatory activity of four Bolivian
Baccharis species (Compositae).” J.
Ethnopharmacol. 2006 Feb; 103(3): 338-44.
Samy,
R., et al. "Therapeutic Potential of Plants as
Anti-microbials for Drug Discovery." Evid Based
Complement Alternat Med. 2010 September; 7(3):
283–294
Morales, G., et al. "Antimicrobial activity
of three Baccharis species used in the
traditional medicine of Northern Chile." Molecules.
2008; 13(4): 790-4.
Betoni, J., et al. "Synergism
between plant extract and antimicrobial drugs used on
Staphylococcus aureus diseases." Mem. Inst.
Oswaldo Cruz. 2006 Jun; 101(4): 387-90.
Hnatyszyn, O., et al. “Argentinian plant extracts with
relaxant effect on the smooth muscle of the corpus
cavernosum of guinea pig.” Phytomedicine. 2003
Nov; 10(8): 669-74.
Gervâo (Stachytarpheta cayennensis)
Lee, J., et
al. "Anti-asthmatic effects of phenylpropanoid
glycosides from Clerodendron trichotomum leaves and
Rumex gmelini herbes in conscious guinea-pigs challenged
with aerosolized ovalbumin." Phytomedicine. 2011
Jan 15;18(2-3):134-42.
Lee, J. H., et al. "The
effect of acteoside on histamine release and arachidonic
acid release in RBL-2H3 mast cells." Arch. Pharm. Res.
2006 Jun; 29(6): 508-13.
Hazekamp, A., et al.
“Isolation of a bronchodilator flavonoid from the Thai
medicinal plant Clerodendrum petasites.” J.
Ethnopharmacol. 2001; 78(1): 45–9.
Sulaiman, M.,
et al. "Antinociceptive and anti-inflammatory effects of
Stachytarpheta jamaicensis (L.) Vahl (Verbenaceae) in
experimental animal models." Med Princ Pract.
2009;18(4):272-9.
Penido, C., et al.
“Anti-inflammatory and anti-ulcerogenic properties of
Stachytarpheta cayennensis (L.C. Rich) Vahl.” J.
Ethnopharmacol. 2006 Mar; 104(1-2): 225-33.
Picão Preto (Bidens pilosa)
Matsumoto,
T., et al. "Effects of Bidens pilosa L. var. radiata
SCHERFF treated with enzyme on histamine-induced
contraction of guinea pig ileum and on histamine release
from mast cells." J
Smooth Muscle Res. 2009 Jun;45(2-3):75-86
Wang,
N. L., et al. "Two neolignan glucosides and
antihistamine release activities from Bidens
parviflora WILLD." Chem. Pharm. Bull. 2006
Aug; 54(8): 1190-2.
Adedapo, A., et al. "Comparison
of the nutritive value and biological activities of the
acetone, methanol and water extracts of the leaves of
Bidens pilosa and Chenopodium album." Acta Pol Pharm.
2011 Jan-Feb;68(1):83-92.
Tobinaga, S., et al.
"Isolation and identification of a potent antimalarial
and antibacterial polyacetylene from Bidens pilosa."
Planta Med. 2009 May;75(6):624-8.
Rojas, J. J.,
et al. "Screening for antimicrobial activity of ten
medicinal plants used in Colombian folkloric medicine: A
possible alternative in the treatment of non-nosocomial
infections." BMC Complement. Altern. Med. 2006
Feb; 6(1):2
Yoshida, N., et al. "Bidens pilosa
suppresses interleukin-1beta-induced cyclooxygenase-2
expression through the inhibition of mitogen activated
protein kinases phosphorylation in normal human dermal
fibroblasts." J. Dermatol. 2006; 33(10): 676-83.
Wu, J., et al. "Investigation of the extracts from
Bidens pilosa Linn. var. radiata Sch. Bip. for
antioxidant activities and cytotoxicity against human
tumor cells." J Nat Med. 2013 Jan;67(1):17-26.
Kviecinski, M., et al. "Brazilian Bidens pilosa
Linné yields fraction containing quercetin-derived
flavonoid with free radical scavenger activity and
hepatoprotective effects." Libyan J Med. 2011 Jan
18;6.
Yerba Mate (Ilex paraguariensis)
Peralta, I., et al. "Prevention of Hydrogen
Peroxide-Induced Red Blood Cells Lysis by Ilex
paraguariensis Aqueous Extract: Participation of
Phenolic and Xanthine Compounds." Phytother Res.
2012 Apr 18.
Fernandes, E., et al. "Yerba mate (Ilex
paraguariensis) enhances the gene modulation and
activity of paraoxonase-2: in vitro and in vivo
studies." Nutrition. 2012
Nov-Dec;28(11-12):1157-64.
Pereira, D., et al.
"Influence of the traditional Brazilian drink Ilex
paraguariensis tea on glucose homeostasis."
Phytomedicine. 2012 Jul 15;19(10):868-77.
Vieira, M., et al. "Phenolic acids and methylxanthines
composition and antioxidant properties of mate (Ilex
paraguariensis) residue." J Food Sci. 2010
Apr;75(3):C280-5.
Wnuk, M., et al. "Evaluation of
the cyto- and genotoxic activity of yerba mate (Ilex
paraguariensis) in human lymphocytes in vitro. Mutat
Res. 2009 Sep-Oct;679(1-2):18-23
Matsunaga, K.,
et al. “Inhibitory action of Paraguayan medicinal plants
on 5-lipoxygenase.” Natural Med. 2000; 54(3):
151–54.
Jatoba
(Hymenaea courbaril)
Cavin, A.,
"Bioactive diterpenes from the fruits of
Detarium microcarpum." J. Nat. Prod. 2006;
69(5): 768-73.
Abdel-Kader, M., et al. “Isolation
and absolute configuration of ent-Halimane diterpenoids
from Hymenaea courbaril from the Suriname rain
forest.” J. Nat. Prod. 2002; 65(1): 11-5.
Yang, D., et al. “Use of caryophyllene oxide as an
antifungal agent in an in vitro experimental
model of onychomycosis.” Mycopathologia. 1999;
148(2): 79–82.
Hostettmann, K., et al.
“Phytochemistry of plants used in traditional medicine.”
Proceedings of the Phytochemical Society of Europe.
Clarendon Press, Oxford. 1995.
Rahalison, L., et
al. “Screening for antifungal activity of Panamanian
plants.” Inst. J. Pharmacog. 1993; 31(1): 68–76.
Verpoorte, R., et al. “Medicinal plants of Surinam.
IV. Antimicrobial activity of some medicinal plants.”
J. Ethnopharmacol. 1987; 21(3): 315–18.
Arrhenius, S.P., et al. “Inhibitory effects of
Hymenaea and Copaifera leaf resins on the
leaf fungus, Pestalotia subcuticulari.”
Biochem. Syst. Ecol. 1983; 11(4): 361–66.
Pau
d'arco (Tabebuia impetiginosa)
Lee, M.,
et al. "Analgesic and anti-inflammatory effects in
animal models of an ethanolic extract of Taheebo, the
inner bark of Tabebuia avellanedae." Mol Med Report. 2012 Oct;6(4):791-6
Suo, M., et al. "Anti-inflammatory constituents from
Tabebuia avellanedae." Fitoterapia. 2012
Dec;83(8):1484-8.
Byeon, S., et al. "In vitro and in
vivo anti-inflammatory effects of taheebo, a water
extract from the inner bark of Tabebuia avellanedae."
J Ethnopharmacol. 2008 Sep 2;119(1):145-52.
Awale, S., et al. ”Nitric oxide (NO) production
inhibitory constituents of Tabebuia avellanedae
from Brazil.” Chem. Pharm. Bull. 2005; 53(6):
710-3.
Hofling, J., et al. "Antimicrobial potential
of some plant extracts against Candida species." Braz
J Biol. 2010 Nov;70(4):1065-8.
Melo e Silva, F.,
et al. "Evaluation of the antifungal potential of
Brazilian Cerrado medicinal plants." Mycoses.
2009 Nov;52(6):511-7.
Pereira, E. M., et al. "Tabebuia
avellanedae naphthoquinones: activity against
methicillin-resistant staphylococcal strains, cytotoxic
activity and in vivo dermal irritability analysis."
Ann. Clin. Microbiol. Antimicrob. 2006 Mar; 5: 5.
Park, B. S., et al. "Antibacterial activity of
Tabebuia impetiginosa Martius ex DC (Taheebo)
against Helicobacter pylori." J.
Ethnopharmacol. 2006 Apr; 105(1-2): 255-62.
Park, B. S., et al. “Selective growth-inhibiting effects
of compounds identified in Tabebuia impetiginosa
inner bark on human intestinal bacteria.” J. Agric.
Food Chem. 2005 Feb; 23;53(4): 1152-7.
Park, B.
S., et al. “Antibacterial activity of Tabebuia
impetiginosa Martius ex DC (Taheebo) against
Helicobacter pylori.” J. Ethnopharmacol. 2005
Dec;
Machado, T. B., et al. “In vitro
activity of Brazilian medicinal plants, naturally
occurring naphthoquinones and their analogues, against
methicillin-resistant Staphylococcus aureus.”
Int. J. Antimicrob. Agents. 2003; 21(3): 279-84.
Portillo, A., et al. “Antifungal activity of Paraguayan
plants used in traditional medicine.” J.
Ethnopharmacol. 2001; 76(1): 93–8.
Nagata, K.,
et al. “Antimicrobial activity of novel
furanonaphthoquinone analogs.” Antimicrobial Agents
Chemother. 1998; 42(3): 700–2.
Binutu, O. A., et
al. “Antimicrobial potentials of some plant species of
the Bignoniaceae family.” Afr. J. Med. Sci.
1994; 23(3): 269–73.
Giuraud, P., et al. “Comparison
of antibacterial and antifungal activities of lapachol
and b-lapachone.” Planta Med. 1994; 60: 373–74.
Guaco (Mikania guaco)
Soares, L., et al.
"Preparation of dry extract of Mikania glomerata
Sprengel (Guaco) and determination of its coumarin
levels by spectrophotometry and HPLC-UV." Molecules. 2012 Aug 29;17(9):10344-54.
Gasparetto, J., et al. "Development and validation of
two methods based on high-performance liquid
chromatography-tandem mass spectrometry for determining
1,2-benzopyrone, dihydrocoumarin, o-coumaric acid,
syringaldehyde and kaurenoic acid in guaco extracts and
pharmaceutical preparations." J Sep Sci. 2011
Apr;34(7):740-8
Freitas, T., et al. "Effects of
Mikania glomerata Spreng. and Mikania laevigata Schultz
Bip. ex Baker (Asteraceae) extracts on pulmonary
inflammation and oxidative stress caused by acute coal
dust exposure." J Med Food. 2008 Dec;11(4):761-6
Graca, C., et al. "In vivo assessment of safety and
mechanisms underlying in vitro relaxation induced by
Mikania laevigata Schultz Bip. ex Baker in the rat
trachea." J Ethnopharmacol. 2007 Jul
25;112(3):430-9.
dos Santos, S. C., et al. "LC
characterisation of guaco medicinal extracts, Mikania
laevigata and M. glomerata, and their effects
on allergic pneumonitis." Planta Med. 2006 Jun;
72(8): 679-84.
Soares de Moura, R., et al.
“Bronchodilator activity of Mikania glomerata
Sprengel on human bronchi and guinea-pig trachea.”
J. Pharm. Pharmacol. 2002; 54(2): 249-56.
Fierro, I. M., et al. “Studies on the anti-allergic
activity of Mikania glomerata.” J.
Ethnopharmacol. 1999; 66(1): 19-24.
Leite, M. G.
R., et al. “Actividade bronchodilatora de Mikania
glomerata, Justicia pectoralis e Torresea
cearensis." Simposio de Plantas Medicinais do
Brazil. December 1992. Curitiba. Resumos. p. 21.
Oliveira, F., et al. “Caraterizacao cromatograpfica do
extracto fluido de Mikania glomerata Sprengel.”
Simposio de Plantas Medicinais do Brazil.
December 1992. Curitiba. Resumos. p. 96.
Sinus-complex 120 Cápsulas de 650 mg Preço: 42.20€ . Portes gratuitos se for antecipadamente pago por MB ou transferência. À cobrança + 6.00€ - só para Portugal
Encomendas pelo telf:. 21 726 12 09 ou por email:vidarmonia.geral@vidarmonia.pt
Preços incluem IVA a taxa legal em vigor - preços podem ser alterados sem aviso prévio. Material sujeito a disponibilidade de stock.